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Jason K. Sello

Visiting Associate Professor 2013-2014 Associate professor, Department of Chemistry, Brown University
The trailblazers in human, academic, scientific and religious freedom have always been in the minority… It will take such a small committed minority to work unrelentingly to win the uncommitted majority. Such a group may transform America’s greatest dilemma into her most glorious opportunity.
— Dr. Martin Luther King Jr.

Background

Jason K. Sello is an associate professor in the Department of Chemistry at Brown University. He earned a PhD in biophysics from Harvard University in 2002 and a BS in biology from Morehouse College in 1997.

Interests

In his independent career, Sello has been synergistically using experimental methods from chemistry, molecular biology, biochemistry, and genomics to develop new anti-infectives and biotechnology platforms for the conversion of plant biomass to biofuels and commodity chemicals. At MIT, he worked collaboratively with Prof. Robert T. Sauer in the Department of Biology on antibacterial agents that act by critically perturbing protein turnover in bacteria.

News Items

Sample Work

  • Publication

    Study of PcaV from Streptomyces coelicolor Yields New Insights into Ligand-Responsive MarR Family Transcription Factors

    Davis, J. R., Brown, B. L., Page, R., Sello, J. K. (2013) “Study of PcaV from Streptomyces coelicolor Yields New Insights into Ligand-Responsive MarR Family Transcription Factors”. Nucleic Acids Research. 41: 3888-900. PMID: 23396446

  • Publication

    Genome Sequence of Streptomyces viridosporus T7A ATCC 39115, a Lignin-Degrading Actinomycete

    Davis, J. R., Goodwin, L., Teshima, H., Detter, C., Tapia, R., Han, C., Huntemann, M., Wei, C.-L., Han, J., Chen, A, Kyrpides, N., Mavrommatis, K., Szeto, E., Markowitz, V., Ivanova, N, Mikhailova, N., Ovchinnikova, G., Pagani, I., Pati, A., Woyke, T., Pitluck, S., Peters, L., Nolan, M., Land, M., Sello, J.K. (2013) “Genome Sequence of Streptomyces viridosporus T7A ATCC 39115, a Lignin-Degrading Actinomycete”. Genome Announcements, 1(4): e00416-13. PMID: 23833133.

  • Publication

    Antibacterial of and Resistance to Small Molecule Inhibitors of the ClpP Peptidase

    Compton, C. L., Schmitz, K. R., Sauer, R. T. Sello, J. K. (2013) “Antibacterial of and Resistance to Small Molecule Inhibitors of the ClpP Peptidase”. ACS Chemical Biology, Epub Ahead of Print. PMID: 24047344

  • Publication

    A retrograde trafficking inhibitor of ricin and shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses

    Nelson, C., Carney, D. W., Derdowski, A, Lipovsky, A, Gee, G., O’Hara, B., Williard, P., DiMaio, D., Sello, J. K., Atwood, W. (2013) “A retrograde trafficking inhibitor of ricin and shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses”. mBio, accepted.

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